Peer-Reviewed
Muyskens JB, Winbush R, Foote DM, Turnbull DW, and Dreyer HC. Essential amino acid supplementation alters the p53 transcriptional response and cytokine gene expression following TKA. J Appl Physiol (1985). 03 SEP 2020.doi.org/10.1152/japplphysiol.00022.2020. link *Journal of Applied Physiology Collections: Translational Control of Muscle Mass. link
Muyskens JB, Foote DM, Bigot N, Strycker LA, Smolkowski K, Kirkpatrick TK, Lantz BA, Shah SN, Mohler CG, and Jewett BA, Owen EC, and Dreyer HC. Cellular and morphologic changes with EAA supplementation before and after total knee arthroplasty. J Appl Physiol (1985). 2019 Aug 1;127(2):531-545. PMID: 31343947. link *Journal of Applied Physiology Collections: Translational Control of Muscle Mass. link
Dreyer HC, Owen EC, Strycker LA, Smolkowski K, Muyskens JB, Kirkpatrick TK, Christie AD, Kuehl K, Lantz BA, Shah SN, Mohler CG, and Jewett BA. Essential amino acid supplementation mitigates muscle atrophy after total knee arthroplasty: A randomized, double-blind, placebo-controlled trial. JBJS Open Access June 04, 2018 doi: 10.2106/JBJS.OA.18.00006. link
Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D’Alessandro A, Nemkov T, Hocker AD1, Prenni JE, Wofle LM, Sindt NM, Lovering AT, Subudhi AW, and Roach RC. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem. 2018 Mar 14. pii: jbc.RA117.000470. doi: 10.1074/jbc.RA117.000470. link
Romero SA, Hocker AD, Mangum JE, Luttrell MJ, Turnbull DW, Struck AJ, Ely MR, Sieck DC, Dreyer HC, Halliwill JR. Evidence of a broad histamine footprint on the human exercise transcriptome. J Physiol. 2016 Sep 1;594(17):5009-23. doi: 10.1113/JP272177. Epub 2016 May 29. link
Muyskens JB, Hocker AD, Turnbull DW, Shah SN, Lantz BA, Jewett BA, Dreyer HC. Transcriptional profiling and muscle cross-section analysis reveal signs of ischemia reperfusion injury following total knee arthroplasty with tourniquet. Physiol Rep. 2016 Jan;4(1). pii: e12671. doi: 10.14814/phy2.12671. link
Hocker AD, RM Boileau, BA Lantz, BA Jewett, JS Gilbert and HC Dreyer. Endoplasmic reticulum stress activation during total knee arthroplasty. Physiol Rep. 2013 Aug 22, DOI: 10.1002/phy2.52. link
Dreyer HC, Strycker SA, Senesac HA, Hocker AD, Smolkowski K, Shah SN, Jewett. Essential amino acid supplementation in patients following total knee arthroplasty. J Clin Invest. 2013; doi:10.1172/JCI70160. link
Banek CT, AJ Bauer, KM Needham, HC Dreyer, JS Gilbert. AICAR administration ameliorates hypertension and angiogenic imbalance in a model of preeclampsia in the rat. Am J Physiol Heart Circ Physiol. 2013 Apr;304(8):1159-65. link
Gilbert JS, CT Banek, SA Babcock Gingery, and HC Dreyer. Diabetes in early pregnancy: getting to the heart of the matter. Diabetes. 2013 Jan;62(1):27-8. link
Gilbert JS, CT Banek, AJ Bauer, A Gingery, and HC Dreyer. Placental and vascular adaptations to training before and during pregnancy in the rat. Am J Physiol Regul Integr Comp Physiol. 2012 Aug;303(4):R376-86. link
Bailey AN, AD Hocker, BR Vermillion, K Smolkowski, SN Shah, BA Jewett, and HC Dreyer. MAFbx, MuRF1, and the Stress Activated Protein Kinases are upregulated in muscle cells during total knee arthroplasty. Am J Physiol Regul Integr Comp Physiol. 2012 Aug;303(4):R376-86. link
Ratchford SM, AN Bailey, HA Senesac, AD Hocker, K Smolkowski, BA Lantz, BA Jewett, JS Gilbert, and HC Dreyer. Proteins regulating cap-dependent translation are downregulated during total knee arthroplasty. Am J Physiol Regul Integr Comp Physiol. 2012 Mar;302(6):R702-11. link
Timmerman KL, JL Lee, S Fujita, S Dhanani, HC Dreyer, CS Fry, MJ Drummond, M Sheffield-Moore, BB Rasmussen, and E Volpi. Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults. Diabetes. 2010 Nov;59(11):2764-71. link
Glynn EL, CS Fry, MJ Drummond, HC Dreyer, S Dhanani, E Volpi, and BB Rasmussen. Muscle Protein Breakdown has a Minor Role in the Protein Anabolic Response to Essential Amino Acid and Carbohydrate Intake Following Resistance Exercise. Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R533-40. link
Timmerman KL, JL Lee, HC Dreyer, S Dhanani, EL Glynn, CS Fry, MJ Drummond, M Sheffield-Moore, BB Rasmussen, and E Volpi. Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling. J Clin Endocrinol Metab. 2010 Aug;95(8):3848-57. link
Dreyer HC, S Fujita, EL Glynn, MJ Drummond, E Volpi, and BB Rasmussen. Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sex. Acta Physiol (Oxf). 2010 May;199(1):71-81. link
Drummond MJ, CS Fry, EL Glynn, HC Dreyer, S Dhanani, KL Timmerman, E Volpi, and BB Rasmussen. Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. J Physiol. 2009 Apr 1;587(Pt7):1535-46. link
Dreyer HC, MJ Drummond, EL Glynn, S Fujita, DL Chinkes, E Volpi, and BB Rasmussen. Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during post-exercise recovery. J Appl Physiol. 2008 Dec;105(6):1967-74. link
Drummond MJ, M Miyazaki, HC Dreyer, B Pennings, S Dhanani, E Volpi, KA Esser, and BB Rasmussen. Expression of growth-related genes in young and old human skeletal muscle following an acute stimulation of protein synthesis. J Appl Physiol. 2009 Apr;106(4):1403-11. link
Fujita S, HC Dreyer, MJ Drummond, EL Glynn, E Volpi, and BB Rasmussen. Essential amino acid and carbohydrate ingestion prior to resistance exercise does not enhance post-exercise muscle protein synthesis. J Appl Physiol. 2009 May;106(5):1730-9. link
Drummond MJ, JA Bell, S Fujita, HC Dreyer, EL Glynn, E Volpi, and BB Rasmussen. Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle. Clin Nutr. 2008 Jun;27(3):447-56. link
Drummond MJ, HC Dreyer, B Pennings, CS Fry, S Dhanani, E Dillon, M Sheffield-Moore, E Volpi, and BB Rasmussen. Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging. J Appl Physiol. 2008 May;104(5):1452-61. link
Drummond MJ, S Fujita, T Abi, HC Dreyer, E Volpi, and BB Rasmussen. Human muscle gene expression following resistance exercise and blood flow restriction. Med Sci Sports Exerc. 2008 Apr;40(4):691-8. link
Dreyer HC, MJ Drummond, B Pennings, S Fujita, EL Glynn, DL Chinkes, S Dhanani, E Volpi, and BB Rasmussen. Leucine-Enriched Essential Amino Acid and Carbohydrate Ingestion Following Resistance Exercise Enhances mTOR Signaling and Protein Synthesis in Human Muscle. Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E392-400. link
Dreyer HC, EL Glynn, HL Lujan, CS Fry, SE DiCarlo, and BB Rasmussen. Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway. J Appl Physiol. 2008 Jan;104(1):27-33. link
Jensky NE, JK Sims, JC Rice, HC Dreyer, and ET Schroeder. The influence of eccentric exercise on mRNA gene expression of skeletal muscle regulators. Eur J Appl Physiol. 2007 Nov;101(4):473-80. link
Fujita S, T Abe, MJ Drummond, JG Cadenas, HC Dreyer, Y Sato, E Volpi, and BB Rasmussen. Blood Flow Restriction during Low-Intensity Resistance Exercise Increases S6K1 Phosphorylation and Muscle Protein Synthesis. J Appl Physiol. 2007 Sep;103(3):903-10. link
Fujita S, HC Dreyer, MJ Drummond, EL Glynn, JG Cadenas, F Yoshizawa, E Volpi, and BB Rasmussen. Nutrient Signalling in the Regulation of Human Muscle Protein Synthesis. J Physiol. 2007 Jul 15;582(Pt 2):813-23. link
Dreyer HC, S Fujita, JG Cadenas, DL Chinkes, E Volpi, and BB Rasmussen. Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. J Physiol. 2006 Oct 15;576(Pt 2):613-24. link
Dreyer HC, ET Schroeder, SA Hawkins, TJ Marcell, KM Tarpenning, AF Vallejo, NE Jensky, G Shaibi, S Spears, R Yamada, and RA Wiswell. Chronic Exercise and Skeletal Muscle Power in Older Men. Appl Physiol Nutr Metab. 2006 Jun;31:190-195. link
Dreyer HC, CE Blanco, FR Sattler, ET Schroeder, and RA Wiswell. Satellite Cell Numbers 24 Hours after a Single Bout of Maximal Eccentric Exercise in Young and Older Men. Muscle & Nerve. 2006 Feb;33:242-253. link
Hawkins SA, ET Schroeder, HC Dreyer, S Underwood, and RA Wiswell. Five year maintenance of bone mineral density in women master runners. Med Sci Sports Exerc. 2003 Jan;35(1):137-144. link
Dreyer HC, SA Hawkins, ET Schroeder, DM Hyslop, and RA Wiswell. The influence of chronic running and HRT in female master athletes. J Clin Exerc Phys. 2002 2:91-95.
Wiswell RA, Hawkins SA, Dreyer HC, and Jaque SV. Maintenance of BMD in older male runners is independent of changes in training volume or VO2Peak. J Geron Med Sci. 2002 Apr;57A:M203-M208. link
Review Articles and Book Chapters
Dreyer HC. Tourniquet Use During Knee Replacement Surgery May Contribute to Muscle Atrophy in Older Adults. Exerc Sport Sci Rev. 2016 Apr;44(2):61-70. doi: 10.1249/JES.0000000000000076. link
Drummond MJ, HC Dreyer, CS Fry, EL Glynn, and BB Rasmussen. Nutritional and Contractile Regulation of Human Skeletal Muscle Protein Synthesis and mTORC1 Signaling. J Appl Physiol. 2009 Apr;106(4):1374-84. link
Dreyer HC, and BB Rasmussen. Rehabilitation Therapies. In: Encyclopedia of Health and Aging. Kyriakos S. Markides (Ed), 2007, pp 493-495.
Dreyer HC, E Volpi. Potential Role of Nutrition in the Pathophysiology and Treatment of Sarcopenia. J Am Coll Nutr. 2005 Apr;24: 140-145. link
Wiswell RA, and HC Dreyer. Myo-inositol and Pangamic Acid. In: Nutritional Ergogenic Aids. I. Wolinsky, J.A. Driskell (Eds.) 2004, pp. 431-444.
Cover Images
Cover Image; Exerc Sport Sci Rev. 2016 Apr;44(2):61-70. link
Cover Image; J Nutrition. 2006 136(8). link
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